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Genetics

Diabetes Genetics 

Team identifies new pathogenic mechanism for diabetes onset in MODY3

December 23, 2022 Er. Gurinderbir Singh 0 Comments

Stem cell–derived beta cell cluster. Credit: Chenglei Tian & Henrik Semb In order to treat patients with diabetes in the

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Diabetes Genetics 

Type 2 diabetes genes linked with gestational diabetes in South Asian women

November 23, 2022 Er. Gurinderbir Singh 0 Comments

Credit: Pixabay/CC0 Public Domain The same complex genetics that contribute to a higher risk of type 2 diabetes may also

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Diabetes Genetics 

MAP3K15 variant found to be a potential target for managing diabetes

November 18, 2022 Er. Gurinderbir Singh 0 Comments

MAP3K15 quantitative trait and disease signatures. (A) Genes with the most similar quantitative trait profiles to MAP3K15 in the UKB,

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Diabetes Genetics 

Promise of better treatment for diabetes in Greenland after discovery of widespread genetic variant

November 16, 2022 Er. Gurinderbir Singh 0 Comments

(A) Screening of variants from whole genome sequencing in MODY genes. Either all variants or only showing moderate or high

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Diabetes Genetics 

Scientists use ‘gentler’ cell transplants to reverse diabetes in mice

November 9, 2022 Er. Gurinderbir Singh 0 Comments

Scientists have used a transplant procedure to apparently cure diabetes in lab mice, without the need for immune-suppressing drugs afterward.

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Diabetes Genetics 

Examining the beta cell whisperer gene and its implications for future diabetes therapy

November 3, 2022 Er. Gurinderbir Singh 0 Comments

Wnt4 expression in islets. a Reporter constructs monitoring Wnt4 expression (Wnt4eGFPCre) and used for lineage tracing (Wnt4eGFPCre; mTmG). Expression pattern

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Diabetes Genetics 

Diabetes-causing gene can be regulated like a rheostat

October 28, 2022 Er. Gurinderbir Singh 0 Comments

Image of a mouse pancreatic islet, regions in the pancreas that contain beta cells which secret insulin. The HASTER regulatory

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Diabetes Genetics 

Researchers identify multiple causal genes that drive type 2 diabetes risk

September 7, 2022 Er. Gurinderbir Singh 0 Comments

Credit: Su et al, Cell Metabolism (2022). DOI: 10.1016/j.cmet.2022.08.014 Researchers from Children’s Hospital of Philadelphia (CHOP) have used advanced three-dimensional

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Diabetes Genetics 

Detection of rare genetic mutation in one family could lead to better diabetes treatments

August 16, 2022 Er. Gurinderbir Singh 0 Comments

Pedigree of the family enriched for diabetes and end-stage renal disease and identification of the ADIPOQ mutation. a The family

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