Team identifies new pathogenic mechanism for diabetes onset in MODY3
Stem cell–derived beta cell cluster. Credit: Chenglei Tian & Henrik Semb In order to treat patients with diabetes in the
Read moreStem cell–derived beta cell cluster. Credit: Chenglei Tian & Henrik Semb In order to treat patients with diabetes in the
Read moreCredit: Pixabay/CC0 Public Domain The same complex genetics that contribute to a higher risk of type 2 diabetes may also
Read moreMAP3K15 quantitative trait and disease signatures. (A) Genes with the most similar quantitative trait profiles to MAP3K15 in the UKB,
Read more(A) Screening of variants from whole genome sequencing in MODY genes. Either all variants or only showing moderate or high
Read moreScientists have used a transplant procedure to apparently cure diabetes in lab mice, without the need for immune-suppressing drugs afterward.
Read moreWnt4 expression in islets. a Reporter constructs monitoring Wnt4 expression (Wnt4eGFPCre) and used for lineage tracing (Wnt4eGFPCre; mTmG). Expression pattern
Read moreImage of a mouse pancreatic islet, regions in the pancreas that contain beta cells which secret insulin. The HASTER regulatory
Read moreCredit: Su et al, Cell Metabolism (2022). DOI: 10.1016/j.cmet.2022.08.014 Researchers from Children’s Hospital of Philadelphia (CHOP) have used advanced three-dimensional
Read morePedigree of the family enriched for diabetes and end-stage renal disease and identification of the ADIPOQ mutation. a The family
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