Team identifies new pathogenic mechanism for diabetes onset in MODY3
Stem cell–derived beta cell cluster. Credit: Chenglei Tian & Henrik Semb In order to treat patients with diabetes in the
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Genetics
Type 2 diabetes genes linked with gestational diabetes in South Asian women
Credit: Pixabay/CC0 Public Domain The same complex genetics that contribute to a higher risk of type 2 diabetes may also
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MAP3K15 variant found to be a potential target for managing diabetes
MAP3K15 quantitative trait and disease signatures. (A) Genes with the most similar quantitative trait profiles to MAP3K15 in the UKB,
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Promise of better treatment for diabetes in Greenland after discovery of widespread genetic variant
(A) Screening of variants from whole genome sequencing in MODY genes. Either all variants or only showing moderate or high
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Scientists use ‘gentler’ cell transplants to reverse diabetes in mice
Scientists have used a transplant procedure to apparently cure diabetes in lab mice, without the need for immune-suppressing drugs afterward.
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Examining the beta cell whisperer gene and its implications for future diabetes therapy
Wnt4 expression in islets. a Reporter constructs monitoring Wnt4 expression (Wnt4eGFPCre) and used for lineage tracing (Wnt4eGFPCre; mTmG). Expression pattern
Read moreDiabetes-causing gene can be regulated like a rheostat
Image of a mouse pancreatic islet, regions in the pancreas that contain beta cells which secret insulin. The HASTER regulatory
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Researchers identify multiple causal genes that drive type 2 diabetes risk
Credit: Su et al, Cell Metabolism (2022). DOI: 10.1016/j.cmet.2022.08.014 Researchers from Children’s Hospital of Philadelphia (CHOP) have used advanced three-dimensional
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Detection of rare genetic mutation in one family could lead to better diabetes treatments
Pedigree of the family enriched for diabetes and end-stage renal disease and identification of the ADIPOQ mutation. a The family
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