Home-grown innovation transforming global infection prevention practice

trophon® technology is an Australian innovation that has transformed the global infection prevention landscape. As the first major breakthrough in high-level disinfection (HLD) for ultrasound probes in more than 20 years, the trophon device is now recognised as the world’s leading automated HLD solution for ultrasound probes. With its proprietary disinfectant mist, the trophon device produces safe and consistent HLD with no handling of toxic or hazardous chemicals.

The trophon family includes both trophon EPR and trophon2 devices which share the same core technology of ‘sonically-activated’ hydrogen peroxide. trophon EPR and trophon2 are equivalent as determined by regulators in terms of efficacy, disinfectant, clinical parameters and independent cycle verification (chemical indicator).

trophon: the global standard of care for ultrasound probe HLD

In Australia, patients will suffer from an estimated 165,000 healthcare-associated infections (HAIs) each year.1 Up to 55% of these HAIs are preventable.2 Medical device reprocessing is one of the key strategies required to help break the chain of infection transmission. With ultrasound probes now used throughout most healthcare departments, automated solutions that offer safe, consistent HLD are necessary to keep patients safe.

Developed by Australian infection prevention company Nanosonics, the trophon device is recognised as the global standard of care for ultrasound probe HLD. With nearly 30,000 units operating worldwide, approximately 98,000 people each day are protected from the risk of healthcare-associated infections with trophon technology.

Redefining chemistry for confidence

trophon technology has redefined chemistry for HLD of ultrasound probes with its proprietary hydrogen peroxide disinfectant, which is ‘sonically-activated’ to create a very fine mist. Each trophon cycle consumes only approximately 2 millilitres of disinfectant, and the mist penetrates shadowed areas formed by crevices, grooves and imperfections on the probe surface. This ensures reproducible efficacy for every probe and every patient with every cycle.

trophon devices also replaced the need for manual handling of toxic, hazardous chemicals by staff performing HLD. For the first time, automated HLD could be performed reproducibly and safely at the patient point of care. As fully enclosed systems, trophon devices mitigate the risk of exposure to hazardous chemicals, fumes and spills that are often associated with wipes and traditional soaking methods, requiring only gloves as PPE. At cycle end, residual hydrogen peroxide is passed through destructors and the by-products are environmentally friendly and safe hydrogen and water.

Masterful microbial defence

The trophon device is the only automated HLD technology for transvaginal, transrectal and surface probes to meet mandatory microbial efficacy test requirements for TGA listing, CE marking and FDA clearance. In addition to mandatory testing, the trophon device goes beyond requirements and eliminates a broad range of pathogens, including sexually transmitted pathogens like human papillomavirus (HPV).3

trophon technology also passes the AOAC 966.04 sporicidal test.4 This test uses two types of carrier device that model challenging medical surfaces likely to be encountered in clinical practice, including surface imperfections and shadowed areas. Ultrasound probes have grooves and crevices that need to be disinfected to the same extent as smooth surfaces, otherwise the next patient may be at increased risk of infection. Unlike other automated HLD solutions, trophon technology has proven efficacy with these challenging surfaces and does not require additional cleaning steps for shadowed areas. trophon devices give you confidence in delivering consistent patient protection even in the most challenging clinical scenarios.

Australian made with local support

Nanosonics is your trusted partner in infection prevention, offering world-leading technology with local manufacturing, R&D and customer support. Nanosonics is proudly Australian-owned with a dedicated local team offering first-class customer service across Australia, with prompt and comprehensive technical support for both trophon EPR and trophon2. Nanosonics also offers a digital traceability solution, AuditPro™, providing facilities with the opportunity to standardise ultrasound infection control compliance. Together, Nanosonics’ trophon technology and AuditPro system arm healthcare professionals with the tools needed to drive compliance and improve patient safety.

Contact Nanosonics today to learn more about trophon technology and AuditPro.


1. Mitchell BG et al. Infect Dis Health 2017;22(3):117—128.

2. Schreiber PW et al. Infect Control Hosp Epidemiol. 2018; 39(11):1277—1295.

3. Nanosonics internal test data & Ryndock E et al. J Med Virol 2016; 88(6):1076—1080.

4. Nanosonics internal test data & Vickery K et al. J Infect Public Health 2014;7(2):153—160.

‘Nanosonics, trophon & AuditPro are trade marks of Nanosonics Limited’

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